CBG (cannabigerol) is a non-intoxicating cannabinoid, and is commonly referred to as the mother of all cannabinoids. It is currently being researched for its potential for mood regulation and anti-inflammatory properties.
(Well, technically this title belongs to its acidic form, CBGa)
CBGa is often referred to as “the mother cannabinoid” as it’s the starting point for the synthesis of other cannabinoids, like THC, CBD etc. CBG Factoid: Because CBG is a minor cannabinoid, researchers often look to young cannabis plants, where it’s higher in abundance!a
Waves of research on cannabis, and particularly minor cannabinoids have been coming in over the last decade. Specifically with CBG, research has been centred around its pharmacological potentials.
Key takeaways from many of these studies have covered CBGs potential in:
a) Managing stress and anxiety. Research has shown that CBG is an effective a-2 adrenoceptor agonist (α-2 agonists can produce relaxation and pain relief effects), and also engages with our 5-HT1A receptor (a receptor engaged with by common SSRIs used for mood regulation).
b) Managing inflammation. Your gut, in particular! Who hasn’t gotten the occasional stress-gut-punch? On a higher level, CBG is being tested for its therapeutic uses in managing more severe cases of gut inflammation, like inflammatory bowel diseases (colitis and Chrohn’s).
c) Anti-viral and neuro-protective uses. Hey, here’s a fun fact: CBG has been shown to the most potent cannabinoid against antibiotic resistant strains of staph. In cells, CBG also inhibits glioblastoma multiforme cells.
You know that saying people throw around about how CBD works better with a little THC? There’s a bit of truth to that*can we say this?*. Studies have shown that unlike CBD, CBG engages with our CB1 and CB2 receptors in a very similar way to THC – without the intoxication. This is helpful for individuals seeking out CBG to elevate their CBD experience, but that are reluctant to use THC due to lifestyle (at work, driving, parenting, etc.) or stigma.